Antibiotics MCQs : This section focuses on the "Antibiotics". These Multiple Choice Questions (MCQs) should be practiced to improve the Antibiotics skills required for various interviews (campus interview, walk-in interview, company interview), placement, entrance exam and other competitive examinations.
Question 1
High yield of chlorotetracyclin requires
A. no aeration
B. continuous aeration
C. aeration which does not affect the yield
D. controlled aeration
Question 2
Media composition for the production of streptomycin is
A. soybean meal, glucose, peptone, malt extract, sodium chloride
B. soybean meal, glucose, peptone, malt extract, ammonium chloride
C. soybean meal, glucose, peptone, malt extract, calcium carbonate
D. soybean meal, glucose, peptone, malt extract, ammonium sulphate
Question 3
Vegetable oil, (corn oil or soybean oil) added in the fermentation medium for penicillin, act as
A. source of nutrients
B. carbon source
C. antifoam agent
D. Both A and C
Question 4
Vegetable oil, (corn oil or soybean oil) added in the fermentation medium for penicillin, act as
A. source of nutrients
B. carbon source
C. antifoam agent
D. both (a) and (c)
Question 5
Which of the following changes occur during first phase of growth of Penicillium chrysogenum?
A. Growth of mycelia occurs
B. Ammonia is liberated in the medium
C. Lactic acid present in the corn steep liquor is utilized at the maximum rate
D. All of the above
Question 6
At normal pH, penicillin remains in
A. aqueous phase
B. solvent phase
C. Both A and B
D. precipitates
Question 7
Media used for the production of chlorotetracyclin consists of
A. sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
B. corn steep liquor, CaCO3 and (NH4)2SO4
C. sugar, CaCO3 and (NH4)2SO4
D. corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
Question 8
Streptomycin is produced by
A. S. griseus
B. S. griseoflavus
C. S. aerofaciens
D. S. ramosus
Question 9
pH of the fermentation medium for chlorotetracyclins is
A. 5-6
B. 6-7
C. 7-8
D. 8-9
Question 10
Which of the following organism(s) produce(s) tetracycline?
A. Steptomyces aureofaciens
B. Steptomyces ramosus
C. Nocardia sulphurea
D. All of the above
Question 11
Antibiotics are typically produced in fed batch reactors because
A. antibiotic yields are generally higher when cells enter the stationary phase
B. the precursors are often toxic to the cells
C. antibiotic yields are generally higher when cell growth slows
D. All of the above
Question 12
Chlorotetracyclin is soluble in
A. organic solvents
B. water
C. ether
D. all of these
Question 13
The yield of the antibiotic depends upon
A. pH of the medium
B. age of the inoculum
C. composition of the medium
D. All of the above
Question 14
At normal pH, penicillin remains in
A. aqueous phase
B. solvent phase
C. both (a) and (b)
D. precipitates
Question 15
At acidic pH, penicillin remains in
A. aqueous phase
B. solvent phase
C. Both A and B
D. precipitates
Question 16
Fermentation medium for oxytetracyclin (terramycin) consist of
A. CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3
B. CSL, (NH4)2 SO4, sodium chloride and CaCO3
C. CSL, starch,(NH4)2 SO4, ammonium chloride and CaCO3
D. CSL,(NH4)2 SO4, ammonium chloride and CaCO3
Question 17
Which of the following organism(s) produce(s) tetracycline?
A. Steptomyces aureofaciens
B. Steptomyces ramosus
C. Nocardia sulphurea
D. All of these
Question 18
Penicillin is recovered after fermentation as
A. potassium penicillin
B. calcium penicillin
C. sodium penicillin
D. penicillin only
Question 19
Which of the following precursor is added in the medium to get penicillin G?
A. Phenyl carbamic acid
B. Phenyl acetic acid
C. Ammonium sulphate
D. Ammonium chloride
Question 20
At acidic pH, penicillin remains in
A. aqueous phase
B. solvent phase
C. both (a) and (b)
D. precipitates
Question 21
Chlorotetracyclin is soluble in
A. organic solvents
B. water
C. ether
D. All of the above
Question 22
Which of the following event occurs during second phase of growth of P. chrysogenum?
A. Synthesis of penicillin is high
B. Mycelial mass increases
C. pH increase
D. Both (a) and (b)
Question 23
Inoculum preparation for the fermentation medium for penicillin takes place on
A. wheat seeds
B. barley seeds
C. rice seeds
D. All of the above
Question 24
The yield of the antibiotic depends upon
A. pH of the medium
B. age of the inoculum
C. composition of the medium
D. all of these
Question 25
Which of the following event occurs during second phase of growth of P. chrysogenum?
A. Synthesis of penicillin is high
B. Mycelial mass increases
C. pH increase
D. Both A and B
Question 26
During which phase of growth of Penicillium chrysogenum maximum antibiotic production takes place
A. during the first phase
B. during the second phase
C. during the third phase
D. same in all the phases
Question 27
Inoculum preparation for the fermentation medium for penicillin takes place on
A. wheat seeds
B. barley seeds
C. rice seeds
D. all of these
Question 28
pH of the fermentation medium for chlorotetracyclins is
A. 05-Jun
B. 06-Jul
C. 07-Aug
D. 08-Sep
Question 29
Which of the following event occurs during third phase of growth of P chrysogenum?
A. Concentration of antibiotic increases in the medium
B. Autolysis of the medium starts
C. Slight rise in pH due to liberation of ammonia
D. All of the above
Question 30
Penicillin is produced by
A. aerobic fermentation
B. anaerobic fermentation
C. aerobic fermentation followed by anaerobic fermentation
D. anaerobic fermentation followed by aerobic fermentation