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Antibiotics MCQ Questions & Answers

Antibiotics MCQs : This section focuses on the "Antibiotics". These Multiple Choice Questions (MCQs) should be practiced to improve the Antibiotics skills required for various interviews (campus interview, walk-in interview, company interview), placement, entrance exam and other competitive examinations.




Question 1

Antibiotics are typically produced in fed batch reactors because

A. antibiotic yields are generally higher when cells enter the stationary phase
B. the precursors are often toxic to the cells
C. antibiotic yields are generally higher when cell growth slows
D. All of the above

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Question 2

Inoculum preparation for the fermentation medium for penicillin takes place on

A. wheat seeds
B. barley seeds
C. rice seeds
D. All of the above

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Question 3

Penicillin is produced by

A. aerobic fermentation
B. anaerobic fermentation
C. aerobic fermentation followed by anaerobic fermentation
D. anaerobic fermentation followed by aerobic fermentation

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Question 4

Which of the following precursor is added in the medium to get penicillin G?

A. Phenyl carbamic acid
B. Phenyl acetic acid
C. Ammonium sulphate
D. Ammonium chloride

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Question 5

Which of the following event occurs during second phase of growth of P. chrysogenum?

A. Synthesis of penicillin is high
B. Mycelial mass increases
C. pH increase
D. Both A and B

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Question 6

At acidic pH, penicillin remains in

A. aqueous phase
B. solvent phase
C. Both A and B
D. precipitates

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Question 7

At normal pH, penicillin remains in

A. aqueous phase
B. solvent phase
C. Both A and B
D. precipitates

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Question 8

During which phase of growth of Penicillium chrysogenum maximum antibiotic production takes place

A. during the first phase
B. during the second phase
C. during the third phase
D. same in all the phases

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Question 9

Streptomycin is produced by

A. S. griseus
B. S. griseoflavus
C. S. aerofaciens
D. S. ramosus

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Question 10

pH of the fermentation medium for chlorotetracyclins is

A. 5-6
B. 6-7
C. 7-8
D. 8-9

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Question 11

Chlorotetracyclin is soluble in

A. organic solvents
B. water
C. ether
D. All of the above

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Question 12

Which of the following changes occur during first phase of growth of Penicillium chrysogenum?

A. Growth of mycelia occurs
B. Ammonia is liberated in the medium
C. Lactic acid present in the corn steep liquor is utilized at the maximum rate
D. All of the above

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Question 13

Vegetable oil, (corn oil or soybean oil) added in the fermentation medium for penicillin, act as

A. source of nutrients
B. carbon source
C. antifoam agent
D. both (a) and (c)

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Question 14

pH of the fermentation medium for chlorotetracyclins is

A. 05-Jun
B. 06-Jul
C. 07-Aug
D. 08-Sep

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Question 15

Chlorotetracyclin is soluble in

A. organic solvents
B. water
C. ether
D. all of these

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Question 16

Which of the following organism(s) produce(s) tetracycline?

A. Steptomyces aureofaciens
B. Steptomyces ramosus
C. Nocardia sulphurea
D. All of the above

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Question 17

The yield of the antibiotic depends upon

A. pH of the medium
B. age of the inoculum
C. composition of the medium
D. All of the above

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Question 18

Which of the following event occurs during second phase of growth of P. chrysogenum?

A. Synthesis of penicillin is high
B. Mycelial mass increases
C. pH increase
D. Both (a) and (b)

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Question 19

Media composition for the production of streptomycin is

A. soybean meal, glucose, peptone, malt extract, sodium chloride
B. soybean meal, glucose, peptone, malt extract, ammonium chloride
C. soybean meal, glucose, peptone, malt extract, calcium carbonate
D. soybean meal, glucose, peptone, malt extract, ammonium sulphate

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Question 20

At acidic pH, penicillin remains in

A. aqueous phase
B. solvent phase
C. both (a) and (b)
D. precipitates

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Question 21

Which of the following organism(s) produce(s) tetracycline?

A. Steptomyces aureofaciens
B. Steptomyces ramosus
C. Nocardia sulphurea
D. All of these

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Question 22

Media used for the production of chlorotetracyclin consists of

A. sugar, corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl
B. corn steep liquor, CaCO3 and (NH4)2SO4
C. sugar, CaCO3 and (NH4)2SO4
D. corn steep liquor, CaCO3, (NH4)2SO4 and NH4 Cl

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Question 23

Which of the following event occurs during third phase of growth of P chrysogenum?

A. Concentration of antibiotic increases in the medium
B. Autolysis of the medium starts
C. Slight rise in pH due to liberation of ammonia
D. All of the above

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Question 24

High yield of chlorotetracyclin requires

A. no aeration
B. continuous aeration
C. aeration which does not affect the yield
D. controlled aeration

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Question 25

Inoculum preparation for the fermentation medium for penicillin takes place on

A. wheat seeds
B. barley seeds
C. rice seeds
D. all of these

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Question 26

Vegetable oil, (corn oil or soybean oil) added in the fermentation medium for penicillin, act as

A. source of nutrients
B. carbon source
C. antifoam agent
D. Both A and C

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Question 27

Penicillin is recovered after fermentation as

A. potassium penicillin
B. calcium penicillin
C. sodium penicillin
D. penicillin only

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Question 28

Fermentation medium for oxytetracyclin (terramycin) consist of

A. CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3
B. CSL, (NH4)2 SO4, sodium chloride and CaCO3
C. CSL, starch,(NH4)2 SO4, ammonium chloride and CaCO3
D. CSL,(NH4)2 SO4, ammonium chloride and CaCO3

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Question 29

At normal pH, penicillin remains in

A. aqueous phase
B. solvent phase
C. both (a) and (b)
D. precipitates

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Question 30

The yield of the antibiotic depends upon

A. pH of the medium
B. age of the inoculum
C. composition of the medium
D. all of these

View Answer