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Cell Cycle MCQ Questions & Answers

Cell Cycle MCQs : This section focuses on the "Cell Cycle". These Multiple Choice Questions (MCQs) should be practiced to improve the Cell Cycle skills required for various interviews (campus interview, walk-in interview, company interview), placement, entrance exam and other competitive examinations.




Question 1

What will happen if a G2 phase cell is fused with an M phase cell?

A. premature chromosome compaction
B. chromosome aggregation
C. gene transcription
D. inhibition of transcription

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Question 2

Resting phase of the cell, where it undergoes growth and DNA replication is called_________

A. Mitosis phase
B. G1 phase
C. Interphase
D. M phase

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Question 3

How many chromatids are there in a duplicated chromosome?

A. One
B. Two
C. Three
D. Four

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Question 4

Cdks bind with __________ , enabling the Cdks to function as enzymes.

A. MPF
B. cyclins
C. histones
D. p53

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Question 5

Name the regulatory component of the cell cycle?

A. Cyclin
B. CDK
C. DNA
D. APC

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Question 6

Which of the following begins when pairs of sister chromatids align in the center of the cell?

A. Anaphase
B. Interphase
C. Metaphase
D. Prophase

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Question 7

Which of the following from a blood clot stimulates the growth of cells in the healing process?

A. EGF
B. PDGF
C. MPF
D. NGF

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Question 8

Each chromosome contains two chromatids by the end of the __________ phase in the life cycle of a human cell.

A. C
B. G2
C. M
D. S

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Question 9

In which phase of the cell cycle does DNA replication take place?

A. Anaphase
B. Metaphase
C. Prophase
D. Interphase

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Question 10

Cyclin binding leads to a change in the _________________ of kinase.

A. pH
B. temperature
C. concentration
D. conformation

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Question 11

Microtubules grow from the poles to kinetochores of each chromatid during

A. prophase
B. metaphase
C. anaphase
D. telophase

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Question 12

Cells which no longer divide (such as certain specialized cells found in the human brain) remain in which phase of the cell cycle?

A. Prophase
B. S phase
C. G0 Phase
D. Gl Phase

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Question 13

The G0 phase is

A. a permanent state of all body cells
B. the state of most cells in an animal body
C. another name for interphase
D. all of the above

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Question 14

What structure forms as a network of protein cables during cell division?

A. Spindle
B. Aster
C. Kinetochore
D. Chromatid

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Question 15

Which of the following is the normal cell cycle, primarily regulated at checkpoints?

A. Metaphase in mitosis
B. Anaphase, G1 boundary
C. G1-S boundary
D. S-G2 boundary

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Question 16

Which process does the M phase of cell cycle start with?

A. Karyokinesis
B. Cytokinesis
C. Interphase
D. Spindle formation

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Question 17

Which of the following triggers the division of activated T lymphocytes?

A. FGF
B. Interlukin 2
C. PDGF
D. Erythroprotein

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Question 18

Name the state where never dividing cells of neurons and skeletal muscle present?

A. G0
B. G1
C. G2
D. M

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Question 19

The phase of mitosis which is associated with the formation of the nuclear envelope, is

A. prophase
B. metaphase
C. anaphase
D. telophase

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Question 20

Which of the following cells are capable of asymmetric cell division?

A. Hepatocytes
B. Epithelial cells
C. Stem cells
D. Neurons

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Question 21

When were the experiments in an effort to understand cell cycle regulation first conducted?

A. 1970s
B. 1980s
C. 1990s
D. 2000s

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Question 22

Sequences that correctly describes the cell cycle is

A. -> G1-> G2 -> S -> mitosis -> cytokinesis ->
B. -> S -> G2 -> mitosis -> cytokinesis -> G1 ->
C. -> G1 ->S -> G2 -> cytokinesis -> mitosis ->
D. ->cytokinesis-> mitosis -> G1 -> S -> G2 ->

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Question 23

Which of these is the correct order of events in the cell cycle?

A. G1 → G2 → S → M
B. G1 → G2 → M → S
C. G1 → S → G2 → M
D. S → M → G1 → G2

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Question 24

In which phase, each chromosome replicates to produce two sister chromatids?

A. Anaphase
B. Interphase
C. Metaphase
D. Prophase

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Question 25

Replication of DNA takes place in S phase.

A. True
B. False

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Question 26

During S phase of the cell cycle, the amount of DNA ______

A. triples
B. remains the same
C. quadruples
D. doubles

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Question 27

The term, not related to mitosis is

A. gametes
B. chromosomes
C. DNA replication
D. somatic cells

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Question 28

At the center of the cell cycle control system is Cdk, a protein that

A. is phosphorylated to become active
B. binds to different cyclins
C. is only active during mitosis
D. manufactures growth factors

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Question 29

The centromeres move toward the poles in __________ .

A. anaphase
B. interphase
C. metaphase
D. prophase

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Question 30

The event(s) which does not occur during interphase, is/are

A. Chromatin condenses
B. Protein Synthesis
C. Organelles replication
D. DNA replication

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Question 31

DNA synthesis involves an increase in chromosome number. True or false?

A. True
B. False

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Question 32

In prokaryotes, just before the cell divides, the two daughter genomes are attached side by side to the

A. cell membrane
B. replication origin
C. centromeres
D. equatorial plate

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Question 33

What is the interval between mitosis and DNA replication?

A. S phase
B. G2 phase
C. G1 phase
D. M phase

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Question 34

In which of the following phase preparations for genome separation are made?

A. C
B. G1
C. G2
D. M

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Question 35

At which of the following check point, mitosis is controlled?

A. G1
B. G2
C. M
D. S

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Question 36

Cdks bind with __________ , enabling the Cdks to function as enzymes.

A. MPF
B. cyclins
C. histones
D. p^53

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Question 37

Which of the following cells do not lack the ability to divide?

A. skin cells
B. nerve cells
C. muscle cells
D. red blood cells

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Question 38

In which of these animals does a haploid cell divide mitotically?

A. Humans
B. Male honey bees
C. Female honey bees
D. Rats

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Question 39

Asynchronous cultures are the ones whose cells are _______________________

A. of different origin
B. randomly distributed through the cell cycle
C. have different genomic content
D. have different nutrient requirements

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Question 40

The cell cycle is controlled in most cells by

A. time (after a certain length of time the cell divides)
B. a series of checkpoints
C. cell size (when the cell reaches a certain size, it divides)
D. different cells exhibit different control strategies

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Question 41

DNA replication is controlled at which of the following checkpoint?

A. G1
B. G2
C. M
D. S

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Question 42

How many hours does the M phase take to complete a cycle?

A. 8hr
B. 1 hr
C. 4 hr
D. 11 hr

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Question 43

How much time of the entire cell cycle is occupied by interphase?

A. 75%
B. 95%
C. 50%
D. 80%

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Question 44

Which of these cells do not divide?

A. Heart cells
B. Melanocytes
C. Osteocytes
D. Liver cells

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Question 45

Which phase of mitosis is associated with chromosomes aligned at the center of the cell and centromeres divide?

A. anaphase
B. interphase
C. metaphase
D. prophase

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Question 46

What is the duration of cell cycle in yeast?

A. 30 minutes
B. 24 hours
C. 90 minutes
D. 48 hours

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Question 47

Which of the following is the primary growth phase of a cell?

A. G1
B. G2
C. M
D. G0

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Question 48

There are ______ major phases in a cell cycle.

A. 1
B. 2
C. 3
D. 4

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Question 49

A nuclear envelope forms around each set of sister chromatids in

A. anaphase
B. metaphase
C. prophase
D. telophase

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Question 50

Which of the following is not the part of Interphase in the cell cycle?

A. S phase
B. G1 phase
C. G2 phase
D. M phase

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Question 51

At the __________ checkpoint, cell growth is controlled.

A. C
B. G1
C. G2
D. S

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Question 52

Which of the following is not a part of a human chromosome in any phase?

A. Centriole
B. Histone
C. Nucleosome
D. Centromere

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Question 53

Meiosis produces cells that have half the genetic content as their parent cells.

A. True
B. False

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Question 54

A centromere is

A. another name for kinetochore
B. the structure to which microtubules attach
C. a constriction on a chromosome bound to a disk
D. All of the above

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Question 55

Which of the following cells do not usually divide but can be induced to divide?

A. red blood cells
B. liver cells
C. hair cells
D. hair follicles

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Question 56

Which phase of mitosis is associated with separation of chromatids?

A. Prophase
B. Metaphase
C. Anaphase
D. Telophase

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Question 57

Name the enzyme which causes ubiquitylation and destruction of cyclin.

A. Acid hydrolases
B. Hyaluronidase
C. Ubiquitin ligase
D. Phosphatase

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Question 58

The term homologous chromosomes

A. refers to replications of the same chromosome
B. is another name for sister chromatids
C. must be haploid
D. means a pair of chromosomes of the same kind, such as sex chromosomes

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Question 59

The spindle forms in the

A. G1 phase
B. G2 phase
C. M phase
D. S phase

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Question 60

The entry of a cell into M phase is initiated by _________________

A. interleukin factor
B. maturation promoting factor
C. transcription factor
D. necrosis factor

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Question 61

Which of these processes is not a part of the cell cycle?

A. Duplication of genome
B. Division into daughter cells
C. Synthesis of cell organelles
D. Degeneration of centrosome

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Question 62

The period between two M phases is called ______

A. interphase
B. prophase
C. prometaphase
D. telophase

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Question 63

Protein synthesis takes place in _____

A. G0 phase
B. G1 phase
C. G2 phase
D. S phase

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Question 64

DNA replication occurs during _________________ of the cell cycle.

A. S phase
B. Interphase
C. G2 phase
D. G0 phase

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Question 65

DNA replication can be monitored by incorporation of ______________________

A. tyrosine
B. thymidine
C. cytosine
D. nitite

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Question 66

Name the cyclin which takes part in M phase?

A. Cyclin E
B. Cyclin A
C. Cyclin D
D. Cyclin B

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Question 67

During which phase, a cleavage furrow is formed in animal cells?

A. C
B. G1
C. G2
D. M

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Question 68

Which of the following statements about mitosis is incorrect?

A. The daughter nuclei are genetically identical to the parent nucleus
B. Chromosomes separate during anaphase due to the interaction of polar microtubules from opposite poles pushing against each other
C. Chromosomes separate during anaphase when the kinetochore microtubules shorten as they depolymerize
D. Chromosomes move to the metaphase plate using motor proteins, a kind of kinesin, attached to spindle fibers

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Question 69

Cyclin dependent kinases are activated by which of the following?

A. Binding to cyclin
B. Binding to cyclin and CDK activating protein kinases
C. Phosphorylation with CDK activating kinase
D. Phosphorylation with tyrosine kinase

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Question 70

In which phase of the cell cycle does centriole duplication take place?

A. S phase
B. G2 phase
C. G1 phase
D. G0 phase

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Question 71

Cells that have stopped dividing and are arrested in a state preceding that of DNA synthesis, are said to be in the__________

A. S phase
B. G1 phase
C. G0 phase
D. G2 phase

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Question 72

How many chromatids does a diploid body cell contain just prior to cell division?

A. 23
B. 46
C. 69
D. 92

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Question 73

Name the process of nuclear division?

A. Ubiquitylation
B. Polymerization
C. Karyokinesis
D. Cytokinesis

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Question 74

In the cell cycle replication of the genome occurs in the

A. G1 phase
B. G2 phase
C. M phase
D. S phase

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Question 75

Which term is used to refer to a period between the cell divisions?

A. M phase
B. G0 phase
C. Interphase
D. Resting phase

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Question 76

The regulatory subunit of maturation-promoting factor (MPF) is called _______________

A. kinase
B. cyclin
C. tetracyclin
D. interleukin

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