Drugs Tissue Binding MCQs : This section focuses on the "Drugs Tissue Binding". These Multiple Choice Questions (MCQs) should be practiced to improve the Drugs Tissue Binding skills required for various interviews (campus interview, walk-in interview, company interview), placement, entrance exam and other competitive examinations.
Question 1
Following is the order in decreasing order of drug binding to the extravascular tissue. Which one is the correct order?
A. Liver > kidney > muscle > lung
B. Liver > muscle > lung > kidney
C. Liver > muscle > kidney > lung
D. Liver > kidney > lung > muscle
Question 2
What is the relation between halogenated hydrocarbon and liver?
A. Halogenated hydrocarbon is a drug for liver problems
B. Halogenated hydrocarbon is nutrition for liver
C. Halogenated hydrocarbon causes hepatotoxicity
D. Halogenated hydrocarbon forms the bile juices in liver
Question 3
What reasons make tissue-drug binding important for drug distribution?
A. Increases the volume of distribution of drugs and results in localization of drug at a specific site
B. Increases the volume of distribution of drugs
C. Results in localization of drugs at a tissue specific site
D. Increases in absorption from the tissue due to concentration increasing
Question 4
Which drug accumulate in adipose tissue?
A. Arsenicals
B. Tetracycline
C. Halogenated hydrocarbons
D. Lipophilic drug
Question 5
Which drug causes brown yellow discoloration of infant’s teeth?
A. Arsenicals
B. Tetracycline
C. Halogenated hydrocarbons
D. Lipophilic drug
Question 6
Which drugs accumulate in liver?
A. Acidic drugs like imipramine
B. Basic drugs like imipramine
C. Halogenated hydrocarbons
D. Chloroquinine
Question 7
Which drugs deposit in hair shafts?
A. Arsenicals
B. Tetracycline
C. Halogenated hydrocarbons
D. Lipophilic drug
Question 8
Which drugs results in distortion of double stranded DNA structure?
A. Arsenicals
B. Quinacrine
C. Halogenated hydrocarbons
D. Lipophilic drug
Question 9
Which metals get accumulated in the kidney?
A. Mercury, cadmium, lead
B. Mercury, cadmium, iron
C. Mercury, lanthanum, lead
D. Mercury, cadmium, fluoride ions
Question 10
Which of the following drugs accumulate in skin?
A. Acidic drugs like imipramine
B. Basic drugs like imipramine
C. Halogenated hydrocarbons
D. Chloroquine
Question 11
Which of the following drugs are responsible for retinopathy?
A. Acidic drugs like imipramine
B. Basic drugs like imipramine
C. Halogenated hydrocarbons
D. Chloroquinine