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Immune Response MCQ Questions & Answers

Immune Response MCQs : This section focuses on the "Immune Response". These Multiple Choice Questions (MCQs) should be practiced to improve the Immune Response skills required for various interviews (campus interview, walk-in interview, company interview), placement, entrance exam and other competitive examinations.




Question 1

B and T lymphocytes arise from _____________

A. hematopoietic stem cells
B. germ cells
C. somatic cells
D. spermatocytes

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Question 2

Which of the following systems protects our body against disease-causing microbes?

A. Immune system
B. Digestive system
C. Excretory system
D. Respiratory system

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Question 3

In cellular immunity, T lymphocytes are responsible for the recognition and killing of foreign invaders. The cells are

A. cytotoxic T lymphocytes (CTL)
B. killer T cells
C. both (a) and (b)
D. none of the above

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Question 4

To elicit the best antibodies to mouse MHC I, it should be injected into a

A. goat
B. mouse of the same genetic background (strain)
C. mouse of a different strain
D. rat

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Question 5

Which type of immune cells are responsible for eradicating intracellular pathogens?

A. natural killer cells
B. mast cells
C. neurons
D. specific lymphocytes

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Question 6

Which of the following group of pathogens always reside intracellularly in the host?

A. virus
B. fungi
C. molds
D. bacteria

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Question 7

What is not required in the innate immune responses?

A. antigen
B. strong immunity
C. pathogen
D. previous contact

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Question 8

Polysaccharides on the surface of infecting microorganisms can also activate complement directly in the absence of

A. antibody via the alternative pathway
B. antigen via the alternative pathway
C. antibody via metabolic pathway
D. none of the above

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Question 9

Which of the following lymphokine(s) is secreted by delayed-type-hypersensitivity cells?

A. Macrophage stimulating factor
B. Migration inhibiting factor
C. Macrophage activating factor
D. All of the above

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Question 10

Adaptive immune responses are more specific that innate immune responses.

A. True
B. False

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Question 11

Which of the following drug acts by stimulating toll-like receptors (TLRs)?

A. Doxorubicin
B. Neosporin
C. Aldara
D. Vimentin

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Question 12

Overactivity of Th cells may result into

A. autoimmunity
B. optimal antibody response
C. optimal cell-mediated response
D. none of the above

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Question 13

Negative phase is observed in

A. secondary humoral response
B. primary humoral response
C. Both A and B
D. None of these

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Question 14

Lens antigens of the eye are

A. cross-reacting antigens
B. sequestrated antigens
C. neoantigens
D. None of these

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Question 15

Induction of tolerance mechanism(s) is/are

A. suppression
B. clonal deletion
C. clonal anergy
D. all of these

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Question 16

What is the result of an abnormal response of the immune system to part of a person's own body?

A. Passive immunity
B. Cancer
C. An allergic response
D. An autoimmune disease

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Question 17

In which of the following cell mediated immunity (CMI) participates?

A. Delayed hypersensitivity reaction
B. Graft versus host reaction
C. Allograft rejection
D. All of the above

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Question 18

Method(s) that can be used to detect CMI is/are

A. migration inhibition
B. target cell destruction factor test
C. skin test for delayed hypersensitivity
D. All of the above

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Question 19

If a person is vaccinated against a disease sometime in the past, which of the following is currently in your body?

A. The disease organism itself and antigens for the disease organism
B. A very high level of antibodies against the disease antigens
C. Memory B lymphocytes for the antigen of this disease organism
D. All of the above

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Question 20

What are the solutions prepared from weakened or dead microorganisms, viruses, or toxins that provide some immunity from diseases?

A. Vaccines
B. Histamines
C. Drugs
D. Antibiotics

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Question 21

Immunosuppressive agent(s) is/are

A. Cyclosporine
B. Methotrexate
C. Anti-lymphocytic serum
D. All of these

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Question 22

Plasma cells produce thousands of __________ that are released into the bloodstream

A. antigens
B. antibodies
C. helper T cells
D. virus fragments

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Question 23

Which of the following is an antimicrobial peptide synthesized by lymphocytes?

A. adhesins
B. condensins
C. defensins
D. complement

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Question 24

A rare disease congenital agammaglobulinemia is caused due to abnormality in __________________

A. humoral antibody
B. cell-mediated immunity
C. acidic/alkaline pH
D. homeostasis

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Question 25

Immunosuppressive agent(s) is/are

A. Cyclosporine
B. Methotrexate
C. Anti-lymphocytic serum
D. All of the above

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Question 26

Innate immune responses are accompanied by inflammation.

A. True
B. False

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Question 27

Induction of tolerance mechanism(s) is/are

A. suppression
B. clonal deletion
C. clonal anergy
D. All of the above

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Question 28

Overactivity of Th cells may result into

A. autoimmunity
B. optimal antibody response
C. optimal cell-mediated response
D. None of these

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Question 29

Immunogenicity

A. depends on the ability of the native antigen to be presented by MHC
B. is usually a property of self antigens such as eye tissue
C. is not a property of antibodies
D. is not a property of haptens

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Question 30

The immune response to a booster vaccine is called a(n)

A. cellular response
B. innate response
C. primary response
D. secondary response

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Question 31

Humoral immunity is mediated by ______________

A. mast cells
B. neutrophils
C. lymphocytes
D. leukocytes

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Question 32

Immunological memory is due to

A. short lived macrophage that can recognize specific pathogens
B. long lived B cells that secrete a specific antibody
C. long lived B cells that secrete a specific antigen
D. short lived helper T cells that signal macrophage to divide

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Question 33

Negative phase is observed in

A. secondary humoral response
B. primary humoral response
C. both (a) and (b)
D. none of the above

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Question 34

The phagocytes can recognize pathogens by means of _____________________

A. necrosis factor
B. complement activation
C. pattern recognition receptors
D. adhesion molecules

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Question 35

Which of the following is an example of autoimmune disease?

A. Rheumatoid arthritis
B. Systemic lupus erythematosus
C. Polyarteritis nodosa
D. All of the above

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Question 36

Which type of interferons is associated with an antiviral innate response?

A. Type I
B. Type II
C. Type III
D. Type IV

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Question 37

What is a protein produced by host cells infected by viruses?

A. Interferon
B. Histamine
C. Antiserum
D. Vaccine

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Question 38

Which of the following is in the lymph nodes of a person battling a cold virus?

A. Huge numbers of white blood cells
B. Trapped viruses that have been roaming the body
C. Lymph ducts that enter and exit the nodes and Lymph fluid
D. All of the above

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Question 39

Which of the following proteins in fruit fly play the major function of dorsoventral polarity of the fly embryo?

A. Toll
B. NEF1
C. Transposons
D. Linker DNA

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Question 40

Which of the following immune cells would have an especially low count in a patient with advanced AIDS?

A. Killer T lymphocytes
B. Helper T lymphocyte
C. B lymphocytes
D. None of these

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Question 41

Antibodies bound to an invading microorganism activate the complement system via

A. classical pathway
B. metabolic pathway
C. Embden Meyerhof pathway
D. Entner-Doudoroff pathway

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Question 42

To detect a humoral immune response to influenza virus, it is possible to measure

A. cytotoxicity of virus-infected cells in tissue culture
B. dividing T cells in the draining lymph nodes
C. plasma cytokine levels
D. serum antibody titer

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Question 43

During exposure to a foreign invader, there are more __________ present in the vertebrate body than before exposure

A. antibodies
B. lymphocytes
C. macrophages and antigens
D. all of these

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