Nucleic Acid Structure MCQs : This section focuses on the "Nucleic Acid Structure". These Multiple Choice Questions (MCQs) should be practiced to improve the Nucleic Acid Structure skills required for various interviews (campus interview, walk-in interview, company interview), placement, entrance exam and other competitive examinations.
Question 1
In DNA sequencing, the primer
A. specifies where the sequence ends
B. specifies where the sequence begins
C. Both A and B
D. generates variety of different sized fragments
Question 2
The chromosome of almost all bacteria is in the shape of
A. an open circle
B. helix
C. a closed circle
D. a linear chromosome
Question 3
In which of the following uracil is present?
A. RNA
B. DNA
C. Both A and B
D. None of these
Question 4
To which of the following adenine always binds?
A. Guanine
B. Cytosine
C. Thymine
D. None of these
Question 5
Guanine always binds to
A. cytosine
B. guanine
C. thymine
D. None of these
Question 6
The function of ribosomes within the cell is
A. to produce ATP
B. to ferment carbohydrates
C. to synthesize proteins
D. All of the above
Question 7
According to base pairing rules the bases of one strand match-up with the bases of the second strand of DNA and the two strands are said to be
A. complementary
B. oppositely charged
C. identical
D. None of these
Question 8
RNA that is complementary to a segment of another RNA molecule to which it will bind is known as
A. missense RNA
B. antisense RNA
C. nonsense RNA
D. None of these
Question 9
Which is not an essential part of a two-component phosphorelay system?
A. Response regulator
B. Sensor kinase
C. Autoinducer
D. None of these
Question 10
The DNA that actually codes for a protein's primary structure in eukaryotes is
A. the entire gene
B. portions of the gene called introns
C. portions of the gene called exons
D. the promoter
Question 11
Stem and loop structures are
A. proteins that help partially denatured enzymes to recover their native configuration
B. structures in DNA caused by inverted repeats
C. structures at the ends of linear eukaryotic DNA molecules
D. the bonds between adjacent DNA nucleotides in the same strand
Question 12
In DNA sequencing, the primer
A. specifies where the sequence ends
B. specifies where the sequence begins
C. both (a) and (b)
D. generates variety of different sized fragments
Question 13
In which of the following uracil is present?
A. RNA
B. DNA
C. Both (a) and (b)
D. None of these
Question 14
The function of ribosomes within the cell is
A. to produce ATP
B. to ferment carbohydrates
C. to synthesize proteins
D. all of these
Question 15
According to Chargaff’s rule, in a DNA molecule ____________
A. The amount of adenine and thymine is equal to the amount of guanine and cytosine
B. The amount of adenine and guanine is equal to the amount of thymine and cytosine
C. The amount of adenine and uracil is equal to the amount of guanine and cytosine
D. The amount of adenine and guanine is equal to the amount of uracil and cytosine
Question 16
Arrangement of nucleotides in DNA can be seen by ____________
A. Ultracentrifuge
B. X-Ray crystallography
C. Light microscope
D. Electron microscope
Question 17
Number of hydrogen bonds between adenine and thymine?
A. 1
B. 2
C. 3
D. 4
Question 18
Number of hydrogen bonds between guanine and cytosine?
A. 1
B. 2
C. 3
D. 4
Question 19
Which of the following is true about Z-DNA helix?
A. It has alternating GC sequences
B. It is a permanent conformation of DNA
C. It tends to be found at the 3’ end of the genes
D. It has fewer base pairs per turn than B-DNA
Question 20
Which of the following leads to disruption of nucleosomal structure?
A. Acetylation
B. Carboxylation
C. Phosphorylation
D. Methylation
Question 21
Which of the following statements is not true about RNA?
A. Does not have a double stranded structure
B. Thymine is present
C. Does not obey Chargaff’s rule
D. The sugar contained in RNA is a ribose
Question 22
Which of the following statements is true?
A. The template strand matches the sequence of the RNA transcript
B. The two strands of DNA run parallel to each other
C. G-C bonds are much more resistant to denaturation than A-T rich regions
D. The common form of DNA is left handed
Question 23
Which one of the following nucleic acids has a left handed helix?
A. M-RNA
B. T-RNA
C. A-DNA
D. Z-DNA
Question 24
Which ratio is constant for DNA?
A. A + G / T + C
B. A + T / G + C
C. A + C / U + G
D. A + U / G + C