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Nucleic Acid Structure MCQ Questions & Answers

Nucleic Acid Structure MCQs : This section focuses on the "Nucleic Acid Structure". These Multiple Choice Questions (MCQs) should be practiced to improve the Nucleic Acid Structure skills required for various interviews (campus interview, walk-in interview, company interview), placement, entrance exam and other competitive examinations.




Question 1

Which of the following leads to disruption of nucleosomal structure?

A. Acetylation
B. Carboxylation
C. Phosphorylation
D. Methylation

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Question 2

The DNA that actually codes for a protein's primary structure in eukaryotes is

A. the entire gene
B. portions of the gene called introns
C. portions of the gene called exons
D. the promoter

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Question 3

The chromosome of almost all bacteria is in the shape of

A. an open circle
B. helix
C. a closed circle
D. a linear chromosome

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Question 4

Arrangement of nucleotides in DNA can be seen by ____________

A. Ultracentrifuge
B. X-Ray crystallography
C. Light microscope
D. Electron microscope

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Question 5

In which of the following uracil is present?

A. RNA
B. DNA
C. Both A and B
D. None of these

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Question 6

Which one of the following nucleic acids has a left handed helix?

A. M-RNA
B. T-RNA
C. A-DNA
D. Z-DNA

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Question 7

The function of ribosomes within the cell is

A. to produce ATP
B. to ferment carbohydrates
C. to synthesize proteins
D. all of these

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Question 8

Guanine always binds to

A. cytosine
B. guanine
C. thymine
D. None of these

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Question 9

Which of the following is true about Z-DNA helix?

A. It has alternating GC sequences
B. It is a permanent conformation of DNA
C. It tends to be found at the 3’ end of the genes
D. It has fewer base pairs per turn than B-DNA

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Question 10

According to base pairing rules the bases of one strand match-up with the bases of the second strand of DNA and the two strands are said to be

A. complementary
B. oppositely charged
C. identical
D. None of these

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Question 11

Which of the following statements is not true about RNA?

A. Does not have a double stranded structure
B. Thymine is present
C. Does not obey Chargaff’s rule
D. The sugar contained in RNA is a ribose

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Question 12

In DNA sequencing, the primer

A. specifies where the sequence ends
B. specifies where the sequence begins
C. Both A and B
D. generates variety of different sized fragments

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Question 13

Which ratio is constant for DNA?

A. A + G / T + C
B. A + T / G + C
C. A + C / U + G
D. A + U / G + C

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Question 14

Number of hydrogen bonds between guanine and cytosine?

A. 1
B. 2
C. 3
D. 4

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Question 15

In which of the following uracil is present?

A. RNA
B. DNA
C. Both (a) and (b)
D. None of these

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Question 16

Which is not an essential part of a two-component phosphorelay system?

A. Response regulator
B. Sensor kinase
C. Autoinducer
D. None of these

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Question 17

RNA that is complementary to a segment of another RNA molecule to which it will bind is known as

A. missense RNA
B. antisense RNA
C. nonsense RNA
D. None of these

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Question 18

According to Chargaff’s rule, in a DNA molecule ____________

A. The amount of adenine and thymine is equal to the amount of guanine and cytosine
B. The amount of adenine and guanine is equal to the amount of thymine and cytosine
C. The amount of adenine and uracil is equal to the amount of guanine and cytosine
D. The amount of adenine and guanine is equal to the amount of uracil and cytosine

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Question 19

To which of the following adenine always binds?

A. Guanine
B. Cytosine
C. Thymine
D. None of these

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Question 20

In DNA sequencing, the primer

A. specifies where the sequence ends
B. specifies where the sequence begins
C. both (a) and (b)
D. generates variety of different sized fragments

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Question 21

Stem and loop structures are

A. proteins that help partially denatured enzymes to recover their native configuration
B. structures in DNA caused by inverted repeats
C. structures at the ends of linear eukaryotic DNA molecules
D. the bonds between adjacent DNA nucleotides in the same strand

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Question 22

The function of ribosomes within the cell is

A. to produce ATP
B. to ferment carbohydrates
C. to synthesize proteins
D. All of the above

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Question 23

Which of the following statements is true?

A. The template strand matches the sequence of the RNA transcript
B. The two strands of DNA run parallel to each other
C. G-C bonds are much more resistant to denaturation than A-T rich regions
D. The common form of DNA is left handed

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Question 24

Number of hydrogen bonds between adenine and thymine?

A. 1
B. 2
C. 3
D. 4

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