Retroviridae MCQs : This section focuses on the "Retroviridae". These Multiple Choice Questions (MCQs) should be practiced to improve the Retroviridae skills required for various interviews (campus interview, walk-in interview, company interview), placement, entrance exam and other competitive examinations.
Question 1
HIV can infect
A. Microglial cells
B. M (membranous) cells
C. CD4 + T lymphocytes
D. All of the above
Question 2
Parasitic infection/s frequently observed in HIV disease is / are.
A. cryptosporidiosis
B. toxoplasmosis
C. isosporiasis
D. All of the above
Question 3
What is the average incubation period for development of AIDS?
A. One year
B. Five years
C. Ten years
D. Twenty years
Question 4
The commonest bacterial infection in HIV disease is/are
A. mycobacterial infection
B. salmonella infection
C. bartonella infection
D. All of the above
Question 5
Viral infections frequently observed in HIV disease is /are
A. herpes simplex
B. varicella- zoster
C. cytomegalo virus
D. All of the above
Question 6
The commonest opportunistic infection in AIDS patient in India is
A. cryptosporidiosis
B. toxoplasmosis
C. tuberculosis
D. cryptococcosis
Question 7
HIV belongs to the family retroviridae and sub-family
A. Oncovirinae
B. Lentivirinae
C. Spumavirinae
D. None of these
Question 8
HIV or Human Immunodeficiency Virus is considered unique because each virus contains:
A. more than 100 copies of the viral genome
B. a genome made up of both DNA and RNA components
C. a viral enzyme known as reverse transcriptase
D. sticky proteins that allow it to bind tightly to host cells
Question 9
Which of the following is transmembrane pedicle antigen of HIV-I?
A. gp 41
B. gp 140
C. gp l20
D. gp 36
Question 10
The confirmatory test(s) for HIV infection is/are
A. virus isolation
B. detection of p24 antigen
C. detection of viral nucleic acid
D. All of the above
Question 11
A viral load test detects the
A. provirus of HIV in infected cells
B. total amount of virus in the infected host
C. number of viruses being released by each infected cell
D. amount of bacteriophage being produced by E. coli cells
Question 12
Fungal infection/s frequently observed in HIV disease is /are:
A. candidiasis
B. cryptococcosis
C. aspergillosis
D. All of the above
Question 13
The screening test/s for diagnosis of HIV infection is/are
A. ELISA
B. Latex agglutination
C. Dot blot assay
D. All of the above
Question 14
The problem(s) associated with development of a vaccine against HIV is/are
A. antibody alone may be insufficient
B. rapid mutation of HIV
C. virus can spread from cell to cell by fusion to produce syncytia
D. All of the above
Question 15
The commonest mode of transmission of HIV is
A. parenteral
B. perintal
C. sexual
D. oral
Question 16
The cells most oftenly infected by HIV are
A. Null cells
B. CD8 + T lymphocytes
C. CD4 + T lymphocytes
D. None of these
Question 17
Which of the following is the spike antigen of HIV-I?
A. gp 120
B. gp 140
C. gp 36
D. gp 41
Question 18
Fungal infection/s frequently observed in HIV disease is /are:
A. candidiasis
B. cryptococcosis
C. aspergillosis
D. all of these
Question 19
HIV can infect
A. Microglial cells
B. M (membranous) cells
C. CD4 + T lymphocytes
D. All of these
Question 20
Parasitic infection/s frequently observed in HIV disease is / are.
A. cryptosporidiosis
B. toxoplasmosis
C. isosporiasis
D. all of these
Question 21
The commonest bacterial infection in HIV disease is/are
A. mycobacterial infection
B. salmonella infection
C. bartonella infection
D. all of these
Question 22
The problem(s) associated with development of a vaccine against HIV is/are
A. antibody alone may be insufficient
B. rapid mutation of HIV
C. virus can spread from cell to cell by fusion to produce syncytia
D. all of these
Question 23
The screening test/s for diagnosis of HIV infection is/are
A. ELISA
B. Latex agglutination
C. Dot blot assay
D. all of these
Question 24
Viral infections frequently observed in HIV disease is /are
A. herpes simplex
B. varicella- zoster
C. cytomegalo virus
D. all of these