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Synthesis of Therapeutic Agents MCQ Questions & Answers

Synthesis of Therapeutic Agents MCQs : This section focuses on the "Synthesis of Therapeutic Agents". These Multiple Choice Questions (MCQs) should be practiced to improve the Synthesis of Therapeutic Agents skills required for various interviews (campus interview, walk-in interview, company interview), placement, entrance exam and other competitive examinations.

Question 1

The recombinant hGH lacks

A. terminal glutamine
B. terminal lysine
C. terminal methionine
D. terminal arginine

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Question 2

The promoter used for cloning HBV surface antigen is

A. galactokinase
B. alcohol dehydrogenase 1
C. β-galactosidase
D. polyhedrin

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Question 3

The gene coding for VP1 is cloned in

A. pMB 9
B. pBR 322
C. pUC 18
D. pUC 19

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Question 4

The two chains are joined together to constitute native insulin using

A. sodium dissulphonate and sodium sulphite
B. sodium dissulphonate and sodium sulphate
C. sodium sulphate and sodium sulphite
D. sodium sulphate only

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Question 5

In India first genetically engineered vaccine against HBV was developed by

A. Ranbaxy Pvt Ltd
B. Shantha Biotechnics Pvt Ltd
C. Dabur Pvt Ltd
D. Glaxo Pvt Ltd

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Question 6

The two chains of insulin can be separated by detaching it from β-galactosidase using

A. hydrogen chloride
B. cyanogen bromide
C. peptidase
D. protease

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Question 7

Human growth hormone (hGH) is secreted by

A. pitutary gland
B. hypothalamus
C. pancreas
D. None of these

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Question 8

Human insulin formed by recombinant DNA technology is known as

A. H insulin
B. R insulin
C. humulin
D. huinsulin

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Question 9

How is human insulin synthesized using recombinant DNA technology?

A. By using chemically synthesized DNA sequences for the two chains separately
B. By isolating DNA from the islets of Langerhans of pancreas
C. By using cDNA for insulin
D. By using chemically synthesized DNA sequences for the complete insulin protein

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Question 10

Chemically synthesized DNA sequences for the two chains are separately inserted into the plasmid pBR 322 by the side of

A. β-Galactosidase
B. galactokinase
C. acid phosphatase
D. glucokinase

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Question 11

Recombinant vaccine for HBV was produced by cloning viral genes in

A. plasmids
B. cosmids
C. autonomously replicating plasmid of yeast
D. phagemids

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Question 12

Foot and mouth disease (FMD) of animals is caused by

A. RNA virus
B. DNA virus
C. bacteria
D. protozoa

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Question 13

Which one of the following capsid protein of picorna virus is immunogenic in nature?

A. VP1
B. VP2
C. VP3
D. VP4

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Question 14

Recombinant vaccine for Hepatitis B virus has been synthesized against which of the following antigen?

A. Viral core antigen (HBcAg)
B. Viral surface antigen (HBsAg)
C. e antigen (HBeAg)
D. All of the above

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Question 15

How many nucleotides are there in Ss RNA molecule of picorna virus causing FMD?

A. 1000
B. 5000
C. 8000
D. 10000

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Question 16

The first therapeutic product formed by means of recombinant DNA technology is

A. human growth hormone
B. insulin
C. hepatitis B vaccine
D. vaccine for foot and mouth disease

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