Protein-Protein Interaction MCQs : Here you will find MCQ Questions related to "Protein-Protein Interaction" in Bioinformatics. These Protein-Protein Interaction MCQ Questions Will help you to improve your Bioinformatics knowledge and will prepare you for various Examinations like Competitive Exams, Placements, Interviews and other Entrance Exmaniations.
Question 1
PPIs stands for?
A. Protein-powerinteractions
B. Protein–protein interactions
C. Protein–people interactions
D. Protein–processes interactions
View Answer
Ans : B
Explanation: Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by interactions that include electrostatic forces, hydrogen bonding and the hydrophobic effect.
Question 2
The recruitment of signaling pathways through PPIs is called?
A. unisignal transduction
B. bisignal transduction
C. signal transduction
D. lateral transduction
View Answer
Ans : C
Explanation: The activity of the cell is regulated by extracellular signals. Signal propagation inside and/or along the interior of cells depends on PPIs between the various signaling molecules. The recruitment of signaling pathways through PPIs is called signal transduction
Question 3
A protein may be carrying another protein is known as?
A. Muscle transport
B. Cell transport
C. Signal transport
D. Membrane transport
View Answer
Ans : D
Explanation: A protein may be carrying another protein (for example, from cytoplasm to nucleus or vice versa in the case of the nuclear pore importins).
Question 4
In many biosynthetic processes enzymes interact with each other to produce small compounds or other macromolecules.
A. TRUE
B. FALSE
C. Can be true or false
D. Can not say
View Answer
Ans : A
Explanation: True, In many biosynthetic processes enzymes interact with each other to produce small compounds or other macromolecules
Question 5
Nucleic acid programmable protein array system was first developed by LaBaer and colleagues in?
A. 2003
B. 2004
C. 2005
D. 2006
View Answer
Ans : B
Explanation: Nucleic acid programmable protein array system was first developed by LaBaer and colleagues in 2004 by using in vitro transcription and translation system.
Question 6
There exist three types of interactions between domains. Which of the following is not one of them?
A. Stable complex
B. Transient interaction
C. Multi-domain protein
D. Unstable interaction
View Answer
Ans : D
Explanation: Interactions between domains determine the structure of multidomain proteins, in which there are several domains on one polypeptide chain. Given that all proteins consist of domains, interactions between domains also occur between the proteins that are permanently associated in stable complexes and proteins that interact transiently, but also exist independently of each other.
Question 7
Interactions between proteins can be predicted computationally by looking for sets of genes that occur as a _______
A. single gene in at least one genome
B. multiple genes in at least one genome
C. multiple genes in various genomes
D. single gene in various genomes
View Answer
Ans : A
Explanation: Interactions between proteins can be predicted computationally by looking for sets of genes that occur as a single gene in at least one genome. Or it can be done by looking for prokaryotic genes that have conserved adjacent gene order across several genomes.
Question 8
Correlation of gene expression for pairs of transiently interacting proteins is ______ compared to randomly chosen pairs of proteins.
A. not significant
B. only marginally significant
C. totally significant
D. significant to much extent
View Answer
Ans : B
Explanation: In prokaryotes, genes are co-regulated if they are a member of the same operon, and many proteins that are members of the same stable complex are part of the same operon. For instance, Ouzounis and Karp determined that over 90% of the enzymes that are in stable complexes in E. coli metabolic pathways are adjacent on the E. coli chromosome.
Question 9
Domains that are part of a multidomain protein are ______
A. nethier co-regulated nor colocalized
B. not co-regulated but colocalized
C. co-regulated and but not colocalized
D. co-regulated and colocalized
View Answer
Ans : D
Explanation: Therefore, members of stable complexes as well as consecutive enzymes may be involved in gene fusions. However elements of signal transduction chains are seldom part of the same gene, for instance, as it is an essential part of their function that they can be regulated and localized independently
Question 10
SH2 domains are structurally composed by three-stranded twisted beta sheet sandwiched flanked by two alpha-helices.
A. TRUE
B. FALSE
C. Can be true or false
D. Can not say
View Answer
Ans : A
Explanation: True, SH2 domains are structurally composed by three-stranded twisted beta sheet sandwiched flanked by two alpha-helices.